Here are 10 recent studies on gastroenterology and endoscopy-related issues.
1. No significant difference exists between CTC and colonoscopy polyp size. CT colonography polyp size is not significantly different from colonoscopy polyp size, according to research findings published in the journal Clinical Gastroenterology and Hepatology. For their study, researchers studied 56 polyps. They found there were no significant differences between CTC polyp size, real-time colonoscopy size estimation or probe measurement.
2. Bariatric surgery is more effective than dieting for glucose control. Researchers at Duke University Medical Center and St. Luke's and Roosevelt Hospital Center, Columbia University, found that obese people with Type 2 diabetes undergoing GBP surgery have much lower levels of circulating branched-chain amino acids and the aromatic amino acids phenylalanine and tyrosine, compared with obese patients with diabetes who lost an equal amount of weight by following a diet.
3. Childhood cancer therapy patients are at increased risk of GI complications. Patients who underwent cancer therapy during childhood are at increased risk of experiencing GI complications later in their lives, according to research published in the journal Gastroenterology. For their study, researchers analyzed cases from a study of 14,358 childhood cancer survivors who were diagnosed from 1970-1986. Researchers found survivors were at increased risk of late-onset complications of the upper GI tract, liver and lower GI tract, compared to their siblings.
4. Breast, ovarian cancer drug could help treat colorectal cancer. A new study from the University of Michigan Comprehensive Cancer Center suggests a class of drugs that has shown promise for breast and ovarian cancer patients with BRCA gene mutations may also benefit certain colorectal cancer patients, according to a U-M Health news report. The class of drugs, called PARP inhibitors, fights against tumors with a specific mutation in the MRE11 gene.
5. Office desk jobs double colon cancer risk. Individuals who work an office desk job for 10 years or more have a higher risk of developing colon cancer than those who lead more active lifestyles, according to research published in the American Journal of Epidemiology. For their study, researchers assessed 918 colon cancer cases and more than 1,000 controls. Individuals who were sedentary for at least 10 years also had a 44 percent increased risk of developing rectal cancer.
6. Cancer from Barrett's Esophagus is less prevalent than previously thought. Patients with nondysplastic Barrett's esophagus have a lower incidence of dysplasia and esophageal adenocarcinoma than previously reported, according to a study published in Clinical Gastroenterology and Hepatology. Researchers examined patients with Barrett's esophagus and followed up for a mean of 5.52 years. These results show a lower incidence of dysplasia and EAC among patients with NDBE than previously reported.
7. Gastrointestional problems are common among endurance athletes. A presenter at the American College of Sports Medicine's 15th annual Health & Fitness Summit & Exposition reported that gastrointestinal problems are some of the most common medical complaints of endurance athletes, according to an ACSM news release. Research shows 30-81 percent of distance runners experience some type of GI disturbance.
8. IBD patients experience a higher incidence of coronary artery disease. Patients with inflammatory bowel disease may be at higher risk of coronary artery disease, according to a study published in the American Journal of Gastroenterology. Results from the study showed the risk of developing coronary artery disease was high among IBD patients, even though this patient population displayed lower rates of coronary artery disease risk factors (hypertension, diabetes, dyslipidemia and obesity).
9. Adolescents lose significant bone mass after bariatric surgery. Bariatric surgery is associated with significant bone loss in adolescents, according to a study published in Pediatrics. A retrospective case review of 61 adolescents following bariatric surgery showed significant decreases in whole-body BMC and BMD after surgery. Weight loss was responsible for 14 percent of the decrease in BMC in the first year post-surgery.
10. Infants' GERD symptoms do not improve from proton-pump inhibitors. Proton-pump inhibitors do not effectively treat gastroesophageal reflux disease in infants, according to a study published in Pediatrics. Researchers conducted a systematic review of randomized controlled trials and crossover studies involving the efficacy and safety of PPIs in children with GERD. They found that infants' GERD symptoms did not consistently improve from PPIs.
Related Articles on Gastroenterology and Endoscopy:
FDA Approves Fusilev for Colorectal Cancer Patients
New FDA Guidance Aims to Reduce Infections From Endoscopes
Gastroenterologist Marvin Sleisenger Honored With UCSF Award
1. No significant difference exists between CTC and colonoscopy polyp size. CT colonography polyp size is not significantly different from colonoscopy polyp size, according to research findings published in the journal Clinical Gastroenterology and Hepatology. For their study, researchers studied 56 polyps. They found there were no significant differences between CTC polyp size, real-time colonoscopy size estimation or probe measurement.
2. Bariatric surgery is more effective than dieting for glucose control. Researchers at Duke University Medical Center and St. Luke's and Roosevelt Hospital Center, Columbia University, found that obese people with Type 2 diabetes undergoing GBP surgery have much lower levels of circulating branched-chain amino acids and the aromatic amino acids phenylalanine and tyrosine, compared with obese patients with diabetes who lost an equal amount of weight by following a diet.
3. Childhood cancer therapy patients are at increased risk of GI complications. Patients who underwent cancer therapy during childhood are at increased risk of experiencing GI complications later in their lives, according to research published in the journal Gastroenterology. For their study, researchers analyzed cases from a study of 14,358 childhood cancer survivors who were diagnosed from 1970-1986. Researchers found survivors were at increased risk of late-onset complications of the upper GI tract, liver and lower GI tract, compared to their siblings.
4. Breast, ovarian cancer drug could help treat colorectal cancer. A new study from the University of Michigan Comprehensive Cancer Center suggests a class of drugs that has shown promise for breast and ovarian cancer patients with BRCA gene mutations may also benefit certain colorectal cancer patients, according to a U-M Health news report. The class of drugs, called PARP inhibitors, fights against tumors with a specific mutation in the MRE11 gene.
5. Office desk jobs double colon cancer risk. Individuals who work an office desk job for 10 years or more have a higher risk of developing colon cancer than those who lead more active lifestyles, according to research published in the American Journal of Epidemiology. For their study, researchers assessed 918 colon cancer cases and more than 1,000 controls. Individuals who were sedentary for at least 10 years also had a 44 percent increased risk of developing rectal cancer.
6. Cancer from Barrett's Esophagus is less prevalent than previously thought. Patients with nondysplastic Barrett's esophagus have a lower incidence of dysplasia and esophageal adenocarcinoma than previously reported, according to a study published in Clinical Gastroenterology and Hepatology. Researchers examined patients with Barrett's esophagus and followed up for a mean of 5.52 years. These results show a lower incidence of dysplasia and EAC among patients with NDBE than previously reported.
7. Gastrointestional problems are common among endurance athletes. A presenter at the American College of Sports Medicine's 15th annual Health & Fitness Summit & Exposition reported that gastrointestinal problems are some of the most common medical complaints of endurance athletes, according to an ACSM news release. Research shows 30-81 percent of distance runners experience some type of GI disturbance.
8. IBD patients experience a higher incidence of coronary artery disease. Patients with inflammatory bowel disease may be at higher risk of coronary artery disease, according to a study published in the American Journal of Gastroenterology. Results from the study showed the risk of developing coronary artery disease was high among IBD patients, even though this patient population displayed lower rates of coronary artery disease risk factors (hypertension, diabetes, dyslipidemia and obesity).
9. Adolescents lose significant bone mass after bariatric surgery. Bariatric surgery is associated with significant bone loss in adolescents, according to a study published in Pediatrics. A retrospective case review of 61 adolescents following bariatric surgery showed significant decreases in whole-body BMC and BMD after surgery. Weight loss was responsible for 14 percent of the decrease in BMC in the first year post-surgery.
10. Infants' GERD symptoms do not improve from proton-pump inhibitors. Proton-pump inhibitors do not effectively treat gastroesophageal reflux disease in infants, according to a study published in Pediatrics. Researchers conducted a systematic review of randomized controlled trials and crossover studies involving the efficacy and safety of PPIs in children with GERD. They found that infants' GERD symptoms did not consistently improve from PPIs.
Related Articles on Gastroenterology and Endoscopy:
FDA Approves Fusilev for Colorectal Cancer Patients
New FDA Guidance Aims to Reduce Infections From Endoscopes
Gastroenterologist Marvin Sleisenger Honored With UCSF Award