A new study shows that even use of low-dose aspirin increases the risk of gastrointestinal bleeding, which is increased further with use of cardiovascular disease-preventing therapies, such as clopidogrel and anticoagulants, according to an American Gastroenterological Association news release.
The study, published in Clinical Gastroenterology and Hepatology, also found that bleeding risk decreased in patients on proton pump inhibitors.
The risk of major GI bleeding also increased when aspirin was combined with clopidogrel or anticoagulants or in patients with a history of GI bleeding.
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