Dr. Sean Moore receives $1M grant to develop model for healthy pediatric development across the globe

Sean Moore, MD, a pediatric gastroenterologist with Cincinnati Children's Hospital Medical Center, has received a $1 million Phase II grant from Grand Challenges Exploration, a Bill & Melinda Gates Foundation initiative.

The grant will fund Dr. Moore's efforts to develop a mouse model of environmental enteropathy, which refers to the damage done to the gut's lining by fecal contamination in water and food. Environmental enteropathy is a considerable barrier to health pediatric growth and children's responses to vaccinations.

Dr. Moore and his colleagues intend to create a mouse model of environmental enteropathy to understand what happens to children's GI tracts. They hope to eventually create better nutritional interventions and vaccines for children's living in countries with high levels of environmental enteropathy.

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