Orexinergic neurons are inhibited by propofol anesthesia and the orexin signals are involved in arousal regulation from propofol, according to an article in Anesthesia & Analgesia.
Previous studies have shown that activities of orexinergic neurons were inhibited by isoflurane and sevoflurane and the microinjection of orexin facilitated the emergence from volatile anesthesia.
A study was conducted with rats infused with propofol. The loss and return of the righting reflex time were recorded. As a result, the propofol inhibited orexinergic neuron activity.
More Articles on Anesthesia:
80% Inspiratory Oxygen During Surgery Increased Death, Did Not Reduce Infection
45 Statistics on Anesthesiology Compensation
Dr. Dan Rogers Named Chief of Pediatric Anesthesiology at Palms West Hospital
Previous studies have shown that activities of orexinergic neurons were inhibited by isoflurane and sevoflurane and the microinjection of orexin facilitated the emergence from volatile anesthesia.
A study was conducted with rats infused with propofol. The loss and return of the righting reflex time were recorded. As a result, the propofol inhibited orexinergic neuron activity.
More Articles on Anesthesia:
80% Inspiratory Oxygen During Surgery Increased Death, Did Not Reduce Infection
45 Statistics on Anesthesiology Compensation
Dr. Dan Rogers Named Chief of Pediatric Anesthesiology at Palms West Hospital