A study presented at the recent American Pain Society meeting found that tapentadol ER can be used for analgesia in patients with hypertension because it does not significantly affect blood pressure or heart rate, according to a report by Clinical Advisor.
Investigators examined use of tapentadol, which has µ-opioid receptor agonist and norepinephrine reuptake inhibitor activity, for moderate-to-severe chronic osteoarthritis knee pain or low back pain.
There were no significant differences between tapentadol ER and a placebo or oxycodone CR in changes from baseline to endpoint in blood pressure or heart rate.
Read the Clinical Advisor on pain.
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