The results of a new study published in the March 14 issue of the Journal of the American Medical Association indicates patients with infected necrotizing pancreatitis who received endoscopic transgastric necrosectomy had an associated lower risk of major complications compared to patients who had surgical necrosectomy, according to an AMA news release.
The results came out of a preliminary trial of 20 patients conducted by Olaf J. Bakker, MD, of University Medical Center Utrecht, the Netherlands, and colleagues.
They compared the proinflammatory response and clinical outcome of endoscopic transgastric and surgical necrosectomy. The trial was conducted in four hospitals in the Netherlands between August 2008 and March 2010.
Five of the 20 patients died (10 percent of patients in the endoscopy group vs. 40 percent of patients in the surgical necrosectomy group), with all deaths caused by persistent multiple organ failure, according to the researchers. Major complications were also reduced in patients in the endoscopy group (20 percent vs. 80 percent in the surgery group).
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