Second Round of Fecal Testing Reveals Fewer Cancers, Study Says

The positive predictive value for colorectal cancer of second round fecal immunochemical testing is half that of first round testing, according to a study reported in Oncology Report.

The findings, published in the March issue of Gastroenterology, revealed no significant difference in positive predictive value between average risk patients who received a guaiac fecal occult blood test in the first round and those who received a fecal immunochemical test in the first round.

Researchers said, however, that "no large difficulties are to be expected should a switch from a guaiac-based program to a FIT-based program be desired in screening programs currently using guaiac tests."

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