Continued antibiotic resistance indicates a need for new strategies to minimize antibiotic-resistant bacteria and make long- lasting improvement, according to a perspective piece in the New England Journal of Medicine.
The authors group these new strategies into the following five categories:
1. Preventing infection and resistance. One tactic in this category is using automated disinfectant in hospital rooms, according to the study.
2. Refilling antibiotic pipeline by aligning economic and regulatory approaches. Government or non-profit grants can help support antibiotic research.
3. Preserving available antibiotics, slowing resistance. For example, healthcare providers can publicly report antibiotic-use data for benchmarking and reimbursement, the authors wrote.
4. Developing microbe-attacking treatments with diminished potential to drive resistance. Immune-based therapies are one example of microbe-attacking treatments.
5. Developing treatments attacking host targets rather than microbial targets to avoid selective pressure driving resistance. For example, healthcare providers can employ direct moderation of host inflammation in response to infection.
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The authors group these new strategies into the following five categories:
1. Preventing infection and resistance. One tactic in this category is using automated disinfectant in hospital rooms, according to the study.
2. Refilling antibiotic pipeline by aligning economic and regulatory approaches. Government or non-profit grants can help support antibiotic research.
3. Preserving available antibiotics, slowing resistance. For example, healthcare providers can publicly report antibiotic-use data for benchmarking and reimbursement, the authors wrote.
4. Developing microbe-attacking treatments with diminished potential to drive resistance. Immune-based therapies are one example of microbe-attacking treatments.
5. Developing treatments attacking host targets rather than microbial targets to avoid selective pressure driving resistance. For example, healthcare providers can employ direct moderation of host inflammation in response to infection.
More Articles on Multidrug-Resistant Organisms:
Study: Hydrogen Peroxide Vapor Beats Standard Disinfection for Multidrug-Resistant OrganismsJoint Commission, Pfizer to Offer Antimicrobial Stewardship Grant
7 Interventions to Reduce Antibiotic Exposure in Hospitals
