From device manufacturers to providers of surgical tables for orthopedics, here are 16 orthopedic and spine device companies ASC leaders should know:
1. Stryker (Kalamazoo, Mich.). A global medical technologies company, Stryker develops implants for joint surgeries, surgical navigation systems and spinal devices. Stryker was founded in 1941 by Dr. Homer Stryker, who started the company by manufacturing turning frames and walking heels. Today, Stryker's key products include the Mako robot and the Triathlon knee system, and sells its products to ASCs, hospitals and other healthcare facilities. Stryker reported $13.6 billion in annual global sales in 2018, and has experienced 39 consecutive years of sales growth.
2. DePuy Synthes, a Johnson & Johnson Company (Raynham, Mass). DePuy Synthes is a global orthopedic and neurosurgery device manufacturer. The company started as DePuy Manufacturing Company in 1895, and was later acquired by Johnson & Johnson in 1998. Johnson & Johnson acquired Synthes in 2012 and merged it with DePuy to develop the company's orthopedic and spine business. DePuy Synthes products include the Attune knee system, the Sigma high performance partial knee system and the Global FX shoulder system.
3. Medtronic (Dublin, Ireland). Medtronic was founded in 1949 as a medical equipment repair shop. Today, Medtronic is the world's largest medical technology company. Medtronic manufactures products for general surgery, cardiovascular surgery, spine surgery and more. Medtronic's key products include the Mazor X spine surgery robot and the StealthStation S8 neurosurgery navigation system.
4. Smith & Nephew (London, England). Smith & Nephew's beginnings date back to 1856, when founder Thomas James Smith and his nephew opened a pharmacy in Hull, England. By 1990, Smith & Nephew had grown into a global medical device manufacturer, and has expanded to include endoscopy, orthopedics and wound management products. Smith & Nephew's products include the Journey knee, Birmingham hip and Navio surgical system robotic technology for knee surgery. Smith & Nephew reported that its 2018 group revenue was $4.9 billion .
5. Zimmer Biomet (Warsaw, Ind.). Zimmer Biomet was founded in 1927 and provides medical devices to surgeons in over 100 countries. Notably, Zimmer Biomet's portfolio includes the Persona personalized knee, NexGen knee solution, sports medicine and spine solutions as well as the ROSA Knee System. Zimmer Biomet also partnered with Apple last year to introduce the mymobility app for the Apple Watch for patients recovering from surgery.
6. NuVasive (San Diego, Calif.). NuVasive is known for its lateral spine surgery system, the eXtreme Lateral Interbody Fusion. NuVasive also offers the X360, a comprehensive approach to lateral single-position surgery designed to improve OR efficiency. Finally, the company is developing a robotic technology, Pulse, that it plans to unveil in September. Across its 25+ locations worldwide, NuVasive has 2,600 employees, and reports $1.101 billion in annual revenue.
7. Neo Medical (Switzerland). Neo aims to optimize the traditional 200-plus screw size variations for spinal procedures to 14 screws that can provide the equivalent standard of care. The New Pedicle Screw System is a five-instrument system that allows surgeons the same capabilities as the 60-insturment traditional sets.
8. RTI Surgical (Marquette, Mich.). RTI Surgical began in 1998 as a University of Florida tissue bank and grew to a global surgical implant company that produces synthetic and biologic implants. The company offers orthobiologics, spine, extremities and sports medicine lines. Last year, RTI acquired Paradigm Spine and the coflex device for interlaminar stabilization. RTI Surgical reported revenue of $69.7 million in the first quarter of 2019, including $2 million through its acquisition of Paradigm Spine.
9. Flower Orthopedics (Horsham, Pa.). Flower Orthopedics was founded in 2012 to produce foot and ankle surgical solutions for ambulatory and acute care settings nationwide. Over the past five years, Flower Orthopedics' single-use products have been used in approximately 16,000 surgical cases. Flower Orthopedics' name derives from its FlowerGroove implant design, which features a locking mechanism that standardizes its screw and instrument offerings.
10. Aurora Spine (Carlsbad, Calif.). Founded in 2013, Aurora Spine specializes in regenerative and minimally invasive technologies. Aurora Spine's product line includes the Relay-C fusion system and the EOS TLIF interbody fusion cage. In 2018, Aurora Spine reported that its revenues had increased 45 percent year over year.
11. Exactech (Gainesville, Fla.). Exactech is a device manufacturer that distributes to more than 25 countries worldwide. The company was founded in 1985 by an orthopedic surgeon with a goal to improve the lives of arthritis patients. Exactech manufactures implants for hip, knee, foot and ankle surgery. Exactech also produces the ExactechGPS system, which is a computer guided surgical navigation system for total joint replacement surgery.
12. Xtant Medical (Belgrade, Mont.). Xtant Medical's business is focused around orthobiologics and spinal fixation systems, including the Axograft and Axle products. Xtant Medical has been a player in the spinal and orthopedic device market for 20 years and reported that its fourth quarter revenues were $18.3 million.
14. Globus Medical (Audubon, Pa.). Globus Medical was founded in 2003 as a musculoskeletal solutions company. Globus Medical focuses on spinal surgery systems and its products include ExcelsiusGPS, a robotic navigation technology developed for spinal procedures. In the first quarter of 2019, Globus Medical reported its sales were $182.9 million.
15. Innovative Medical Products (in Plainville, Conn.). Established in 1983, Innovative Medical Products is a manufacturer of patient positioning devices for orthopedic surgical procedures. Innovative Medical Products' devices include positioners for knee and hip procedures and it also sells a line of patient protective pads.
16. Mizuho OSI (Union City, Calif.) . Founded in 1978, Mizuho OSI began as a medical soft goods company. OSI was acquired by Mizuho Ikakogyo in 2002 and became Mizuho OSI. Today, Mizuho OSI sells specialized surgical tables for hip and knee replacement surgery, as well as spine and orthopedic trauma surgery.