A new study found cyclosporine was no more effective than infliximab in patients with acute, severe ulcerative colitis refractory to intravenous steroids, according to a report by Internal Medicine News.
The randomized, multicenter open-label trial, presented at Digestive Disease Week, sought to determine whether treatment failure was less frequent with cyclosporine than with infliximab.
About 25 percent of patients with ulcerative colitis have acute severe ulcerative colitis. While intravenous corticosteroids are the primary therapy, 40 percent of patients are refractory to them, leaving cyclosporine or infliximab, as the only two medical options to avoid colectomy.
Read the Internal Medicine News report on ulcerative colitis.
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