A scoring system using five variables can accurately categorize patients with Clostridium difficile infection by their predicted response to therapy, according to a study in BMC Infectious Diseases.
Researchers assessed the correlation of clinical and laboratory variables measured at the time of CDI diagnosis with CDI patients' treatment response. A combination of five factors had the best discrimination and correlation with cure. The five-part ATLAS score includes the following:
• Age
• Treatment with systemic antibiotics
• Leukocyte count
• Albumin
• Serum creatinine as a measure of renal function
The ATLAS score effectively separated patients into 11 groups by their likely treatment outcome.
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Researchers assessed the correlation of clinical and laboratory variables measured at the time of CDI diagnosis with CDI patients' treatment response. A combination of five factors had the best discrimination and correlation with cure. The five-part ATLAS score includes the following:
• Age
• Treatment with systemic antibiotics
• Leukocyte count
• Albumin
• Serum creatinine as a measure of renal function
The ATLAS score effectively separated patients into 11 groups by their likely treatment outcome.
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