Reduction of tidal volume in mechanically ventilated patients undergoing elective cardiac surgery could improve secondary outcomes, according to a report published in Anesthesiology.
Reduction of tidal volume did not significantly shorten time to extubation but could still be beneficial to patients undergoing elective cardiac surgery, according to the study's abstract. Researchers conducted a single-center randomized controlled trial in 149 patients undergoing elective cardiac surgery and compared ventilation with 6 versus 10 mL/kg tidal volume. Ventilator settings were applied immediately after anesthesia induction and continued throughout surgery and the subsequent ICU stay.
While the primary endpoint of the study was time to extubation, secondary endpoints included the proportion of patients extubated at 6 hours and indices of lung mechanics and gas exchange. Patient clinical outcomes were also examined. The researchers found a higher proportion of patients in the low tidal volume group were free of any ventilation at 6 hours and fewer patients required reintubation.
Read the study in Anesthesiology on cardiac surgery and ventilation.
Read more on anesthesia:
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Reduction of tidal volume did not significantly shorten time to extubation but could still be beneficial to patients undergoing elective cardiac surgery, according to the study's abstract. Researchers conducted a single-center randomized controlled trial in 149 patients undergoing elective cardiac surgery and compared ventilation with 6 versus 10 mL/kg tidal volume. Ventilator settings were applied immediately after anesthesia induction and continued throughout surgery and the subsequent ICU stay.
While the primary endpoint of the study was time to extubation, secondary endpoints included the proportion of patients extubated at 6 hours and indices of lung mechanics and gas exchange. Patient clinical outcomes were also examined. The researchers found a higher proportion of patients in the low tidal volume group were free of any ventilation at 6 hours and fewer patients required reintubation.
Read the study in Anesthesiology on cardiac surgery and ventilation.
Read more on anesthesia:
-Colorado Court Upholds Opt-Out From Federal Anesthesia Requirement
-7 Statistics on Anesthesiologist Salary by City
-Bill Would Allow Inspections of Delaware Facilities That Perform Procedures With Anesthesia