Gabapentin does not decrease pain before and after patients undergo primary total knee arthroplasty, according to a study reported in Anesthesiology News.
The study showed no significant difference after surgery in the use of morphine, pain scores or length of stay in the hospital between patients who were randomly assigned to gabapentin or a placebo.
The study examined 101 patients who were randomized to gabapentin or a placebo before and after TKA. Perioperatively, the patients received the study medication orally, as well as a standard spinal anesthesia with hyperbaric bupivacaine combined with fentanyl. Postoperatively, the patients were given IV morphine for three days and 200 mg of gabapentin or placebo orally every eight hours.
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The study showed no significant difference after surgery in the use of morphine, pain scores or length of stay in the hospital between patients who were randomly assigned to gabapentin or a placebo.
The study examined 101 patients who were randomized to gabapentin or a placebo before and after TKA. Perioperatively, the patients received the study medication orally, as well as a standard spinal anesthesia with hyperbaric bupivacaine combined with fentanyl. Postoperatively, the patients were given IV morphine for three days and 200 mg of gabapentin or placebo orally every eight hours.
Related Articles on Anesthesia:
Type of General Anesthesia Does Not Increase Delirium in Post-Op Period
World-Renowned Anesthesiologists Debate Over Cause of Michael Jackson's Death
Study: Effective Propofol Dose Lower for Obese Children