10 most commonly prescribed pain medications 

Hydrocodone-acetaminophen was the most commonly prescribed pain medication in 2022, according to a recent report from Definitive Healthcare. 

Here are the top 10 pain medications prescribed in 2022, according to Definitive Healthcare. 

1. Hydrocodone-acetaminophen
2. Ibuprofen
3. Tramadol
4. Oxycodone-acetaminophen
5. Oxycodone 
6. Aspirin 
7. Acetaminophen-codeine
8. Morphine sulfate
9. Butalbital-acetaminophen-caffe
10. Acetaminophen