A study published in the Journal of Allergy and Clinical Immunology identified a potential marker of disease activity for eosinophilic esophagitis.
Patricia C. Fulkerson, MD, PhD, assistant professor of pediatrics at Cincinnati Children's Hospital Medical Center, was the study's senior author.
Here are five points:
1. The researchers investigated a precursor cell to eosinophilis, a lineage-committed eosinophil progenitor, as a potential marker.
2. The researchers found elevated EoP levels in the blood of pediatric patients with active EoE disease, suggesting a promising, blood-based marker.
3. This clinical study is the first to investigate EoP levels in patients with EoE.
4. The authors emphasize additional research is needed to validate the EoP-based marker before its routine use in clinic.
5. In previous studies, the Cincinnati Center for Eosinophilic Disorders' team at Cincinnati Children's Hospital Medical Center has reported that incidence of EoE is estimated at one out of 1,000 people.