The American Gastroenterological Association published two new evidence-based Crohn's Disease guidelines in Gastroenterology.
The AGA's Clinical Guidelines Committee developed the guidelines to help physicians on two highly-debated issues — managing CD after surgical resection and diagnosing and managing acute liver failure.
The first guideline titled, AGA Institute Guideline on the Management of Crohn's Disease After Surgical Resection, works to help gastroenterologists prevent postoperative disease recurrence as surgical resection is associated with high morbidty rates.
The six guidelines address several treatments including the use of early pharmacological prophylaxis over endoscopy guided treatment; the use of an anti-TNF therapy and/or thiopurines; and the use of mesalamine, budesonide or probiotics.
The full guideline is available here.
The AGA published its recommendations for diagnosing and managing acute liver failure to address differing diagnostic and treatment strategies and predictive models for acute liver failure. The recommendations are titled "AGA Institute Guidelines for the Diagnosis and Management of Acute Liver Failure." The association also drafted the recommendation as ALF is difficult to study in randomized clinical trials.
The eleven guidelines address several strategies like routinely testing all patients for varicella-zoster virus, testing for hepatitis E and suggesting autoantibody testing.
The full guideline is available here.