Patients With Chronic Kidney Disease at Risk for Morbidity, Longer Hospital Stay Following Elective Surgery

A substantial minority of patients with chronic kidney disease undergoing elective orthopedic procedures are at increased risk for prolonged morbidity and hospital stay, according to a study published in the June 2011 issue of Anesthesia & Analgesia.

The researchers chose to study patients undergoing elective orthopedic joint replacement procedures, which represent a large proportion of global surgical procedures and are characterized by highly homogenous anesthetic and surgical practice, according to the study's abstract.

The researchers calculated chronic kidney disease based on the patients' estimated glomerular filtration rate, which is strongly associated with increased cardiovascular risk and all-cause mortality. The study analyzed morbidity differences between patients with CKD and normal preoperative renal function, as well as time to hospital discharge and time to become morbidity-free.

The postoperative morbidity survey was recorded in 526 patients undergoing elective orthopedic surgery. The study revealed preoperative eGFR to be associated with more frequent morbidity and longer hospital stay, independent of age.

Read the abstract on the study in Anesthesia & Analgesia.

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